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Lincoln Burrows, played by Dominic Purcell, is a protagonist of the American television series, Prison Break. The plot of Prison Break revolves around Lincoln Burrows' setup for the murder of the vice president's brother and his brother's plan to help him escape his death sentence. Lincoln's brother, Michael Scofield is played by Wentworth Miller. In episode flashbacks, the teenage Lincoln is played by Max Kirsch, while a younger Michael is portrayed by Hunter Jablonski.

As one of the principal characters, Lincoln plays a prominent role in the series and has appeared in every episode so far. The brother's relationship is frequently explored in the series as their sacrifices for each other form a large part of the plot. In an interview, series creator Paul Scheuring commented that it was "extremely difficult" to cast the roles of Lincoln and Michael. Dominic Purcell was cast for the role just three days before the start of production of the series pilot.